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DSIP is studied because sleep regulation and the peptides involved in it remain scientifically interesting, and because a compound that influences sleep architecture without acting like a conventional sedative would be notable if the effect were reliable

In contrast, metformin is commonly used during pregnancy for diabetes and polycystic ovary syndrome, and is compatible with breastfeeding

Reported side effects in limited human use include mild nausea and dizziness

The United States Food and Drug Administration (FDA) has already approved about 60 peptide-based medications for various indications, while hundreds of other peptides are under active research for their potential implications [17]